Product
name: CD-NP
Sequence:
GLSKGCFGLKLDRIGSMSGLGCPSLRDPRPNAPSTSA
Modifications:
disulfide,
Purity: 95% by
HPLC
Counter
ion: Trifluoacetate
Format: Lyophilized
powder
Description: CD-NP represents a new class
of natriuretic peptide drug that may circumvent the hypotensive nature of BNP
and preserve or augment renal function in the congestive heart failure setting.
CD-NP contains the full-length 22-amino acid human CNP fused to the 15-amino
acid C-terminal tail of Dendroaspis natriuretic peptide (DNP), an endogenous
vasoactive peptide found in the venom of the green mamba.
Usage: For
Scientific Research Use Only, Not for Human Use.
Reference:
J Biol Chem.
Dec 12, 2008; 283(50): 35003–35009.
J Am Coll
Cardiol. 2008 Jul 1; 52(1):60-8.
J Mol Cell
Cardiol. 2011 Jul; 51(1):67-71.
Curr Opin
Investig Drugs. 2010 Mar; 11(3):349-56.
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