CAS #: 86784-80-7
Formula:
C208H344N60O63S2
MW: 4757.52
Sequence:
H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2
Family Description:
CRF (corticotropin-releasing factor) is a 41-peptide produced mainly
in the hypothalamus. The peptide hormone stimulates ACTH release from the
anterior lobe of the pituitary gland. CRF plays an important role in the
endocrine, behavioral, and immune response to stress and probably as well in the
regulation of energy balance. EEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII amide
also corresponds to the sequence of canine, feline, murine, and porcine
CRF.
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