CAS #: 124584-08-3
Formula:
C143H244N50O42S4
MW: 3464.09
Sequence:
H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH
(Disulfide bond)
Family Description:
The secretion of the cardiac hormone BNP-32 is increased considerably
in patients with congestive heart failure, successful medical treatment of this
condition will result in a decrease. Hence it may serve as a humoral marker.
Yandle et al. described a method for determining hBNP in human plasma. Effects
of hBNP infusion in man have been described by Holmes et al and La Villa et al.
Additionally, BNP-32 may act as a
neuropeptide.
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