Sequence:

H-D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH₂

(Disulfide bond)

Family Description:


Vapreotide is a potent octapeptide analog of somatostatin with selectivity for the somatostatin receptor subtypes SSTR-2 and SSTR-5. It is under investigation in the management of various disorders, including esophageal variceal bleeding, gastrointestinal and pancreatic fistulas, acromegaly, carcinoid tumors, and for the prevention of postoperative complications following pancreatic surgery.