Product name: VEGFR-binding peptide VEGF-A
Synonyms: VEGF-A,
Sequence: KLTWQELYQLKYKGI
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Peptide analogues of VEGF have been investigated as modulators of VEGF signaling, and peptide fragments derived from a single VEGFR binding motif of VEGF-A have been used to antagonize VEGF activity.One particularly well-studied VEGFR-binding peptide, designed to mimic the VEGFR binding site on VEGF-A (KLTWQELYQLKYKGI), has been shown to stimulate VEGF signaling and also synergize with soluble VEGF-A to promote increased endothelial cell proliferation and tubule formation.
Usage: For Scientific Research Use Only, Not for Human Use.
Reference:
J Transl Med. 2009;7:41.
Chemistry. 2008;14(14):4164–6.
Proc Natl Acad Sci U S A. 2005;102(40):14215–20.