Product
name: Clavanin-A
Sequence:
VFQFLGKIIHHVGNFVHGFSHVF
Modifications: c-terminal
amide,
Purity: 95% by
HPLC
Counter
ion: Trifluoacetate
Format: Lyophilized
powder
Description: Clavanin A is a special
antimicrobial peptide that acts at the level of the membrane via a pH-dependent
mechanism. At neutral pH, clavanin disrupts biological and model membranes in a
nonspecific manner, causing efflux of large molecules. At mildly acidic
conditions, however, the peptide efficiently kills bacteria by permeabilizing
their membrane most likely by interacting with proteins involved in proton
translocation .
Uniprot
ID: P80710
Usage: For
Scientific Research Use Only, Not for Human Use.
Reference:
FEBS Letters,
Volume 400, Issue 2, 3 January 1997, Pages 158-162
Biochimica et
Biophysica Acta (BBA) - Biomembranes, Volume 1615, Issues 1–2, 2 September 2003,
Pages 84-92
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