Product name: CD8⁺ T-cell epitope NHP-B2

Sequence: SSPQGSPEPL

Purity: 95% by HPLC

Counter ion: Trifluoacetate

Format: Lyophilized powder

Description: We identified an MHC class II-restricted CD4⁺ T-cell epitope and therein an MHC class I-restricted CD8⁺ T-cell epitope (SSPQGSPEPL) that, after prime/boost immunization, protected up to 25% of mice against a lethal lymphoma challenge. Lymphoma-rejecting animals contained MHC multimer-binding CD8⁺ cell within the peripheral blood and displayed in vivo cytolytic activity with specificity for SSPQGSPEPL.

Uniprot ID:

Usage: For Scientific Research Use Only, Not for Human Use.

Reference:


PLoS One. 2013 Oct 10;8(10):e77375.