Product
name: CD8⁺ T-cell epitope
NHP-B2
Sequence:
SSPQGSPEPL
Purity: 95% by
HPLC
Counter
ion: Trifluoacetate
Format: Lyophilized
powder
Description: We identified an MHC class
II-restricted CD4⁺ T-cell epitope and therein an MHC class I-restricted CD8⁺
T-cell epitope (SSPQGSPEPL) that, after prime/boost immunization, protected up
to 25% of mice against a lethal lymphoma challenge. Lymphoma-rejecting animals
contained MHC multimer-binding CD8⁺ cell within the peripheral blood and
displayed in vivo cytolytic activity with specificity for
SSPQGSPEPL.
Uniprot
ID:
Usage: For
Scientific Research Use Only, Not for Human Use.
Reference:
PLoS
One. 2013 Oct 10;8(10):e77375.