Product name: Orexin-A
Synonyms: Hypocretin-1,Hcrt1,
Sequence: QPLPDCCRQKTCSCRLYELLHGAGNHAAGILTL
Modifications: disulfide(1-3,2-4),N-terminal Pyr, C-terminal amide,
Purity: 95% by HPLC
Counter ion: Trifluoacetate
Format: Lyophilized powder
Description: Orexin A (OxA), also known as hypocretin 1, is a regulatory neuropeptide involved in the control of various autonomic and neuroendocrine functions. It appears to have a significant impact on the regulation of trophic hormones secretion by influencing the hypothalamus and the pituitary.
Uniprot ID: O43612
Usage: For Scientific Research Use Only, Not for Human Use.
Reference:
Behavioural Brain Research, Volume 262, 1 April 2014, Pages 8-13.
Neurochemistry International.Volume 63, Issue 8, December 2013, Pages 719–725.
J Neurosci. 2014 May 7;34(19):6495-509.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1842, Issue 3, March 2014, Pages 440-445
Neurology. 2014 Jan 21;82(3):271-8.
Prog Brain Res. 2012;198:5-14.
Pharmacol Rev. 2009 Jun;61(2):162-76.