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카테고리
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Others
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CAT.NO
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LGP-60-018
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PRODUCT
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Recombinant Human Thymosin beta 4
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SIZE
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100ug, 500ug, 1mg
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PRICE
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KRW 285,000, 940,000, 1,560,000
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Technical Parameters
| Synonyms |
Fx |
| Accession |
P62328 |
| GeneID |
7114 |
| Source |
Escherichia coli. |
| Molecular Weight |
Approximately 4.9 kDa, a single non-glycosylated polypeptide chain containing 43 amino acids. |
| Quantity |
100µg/500µg/1000µg |
| AA Sequence |
SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES |
| Purity |
> 97 % by SDS-PAGE and HPLC analyses. |
| Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 μg/ml. |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation |
Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4. |
| Endotoxin |
Less than 1 EU/µg of rHuTβ4 as determined by LAL method. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage |
This material is offered by Korea Lugen Sci for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| SDS-PAGE |
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| Reference |
1. Moon EY, Song JH, Yang KH. 2007. Oncol Res, 16: 507-16.
2. Oh SY, Song JH, Gil JE, et al. 2006. Exp Cell Res, 312: 1651-7.
3. Oh JM, Ryoo IJ, Yang Y, et al. 2008. Cancer Lett, 264: 29-35. |
| Background |
Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ-4 is a major actin regulating peptide and the primary function is to stimulate the productions of T cells, which plays important part of the immune system. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue. |
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첨부파일
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