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카테고리
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Cytokines & Growth Factor
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CAT.NO
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LGP-12-079
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PRODUCT
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GMF-β, Mouse (Murine Glia Maturation Factor beta)
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SIZE
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10ug, 100ug, 250ug
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PRICE
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KRW 285,000, 1,137,000, 1,971,000
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Technical Parameters
| Synonyms |
GMFB |
| Accession |
Q9CQI3 |
| GeneID |
63985 |
| Source |
Escherichia coli. |
| Molecular Weight |
Approximately 16.6 kDa, a single non-glycosylated polypeptide chain containing 141 amino acid residues. |
| Quantity |
10µg/100µg/250µg |
| AA Sequence |
SESLVVCDVA EDLVEKLRKF RFRKETHNAA IIMKIDKDER LVVLDEELEG VSPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H |
| Purity |
> 97 % by SDS-PAGE and HPLC analyses. |
| Biological Activity |
Data not available. |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Endotoxin |
Less than 1 EU/μg of rMuGMF-β as determined by LAL method. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage |
This material is offered by Korea Lugen Sci for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| Reference |
1. Gandhi M, Smith BA, Bovellan M, et al. 2010. Curr Biol, 20: 861-7.
2. Roman AandTombarkiewicz B. 2009. Bioelectromagnetics, 30: 21-8.
3. Ohnishi T, Arita N, Hayakawa T, et al. 1993. Biochem Biophys Res Commun, 193: 518-25.
4. Nakano K, Kuwayama H, Kawasaki M, et al. 2010. Cytoskeleton (Hoboken), 67: 373-82. |
| Background |
The glia maturation factor beta belongs to the actin-binding proteins ADF family, GMF subfamily. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse ADF-H domain. GMF-β is involved in the differentiation, maintenance, and regeneration of the nervous system. It also inhibition of proliferation of tumor cells. |
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첨부파일
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